Mitochondrial inheritance in budding yeast

Traffic. 2001 Jun;2(6):368-74. doi: 10.1034/j.1600-0854.2001.002006368.x.

Abstract

During the past decade significant advances were made toward understanding the mechanism of mitochondrial inheritance in the yeast Saccharomyces cerevisiae. A combination of genetics, cell-free assays and microscopy has led to the discovery of a great number of components. These fall into three major categories: cytoskeletal elements, mitochondrial membrane components and regulatory proteins. These proteins mediate activities, including movement of mitochondria from mother cells to buds, segregation of mitochondria and mitochondrial DNA, and equal distribution of the organelle between mother cells and buds during yeast cell division.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Cell Cycle
  • Cytoskeleton / physiology
  • DNA, Mitochondrial*
  • Microscopy, Video
  • Microtubules / physiology
  • Mitochondria / physiology*
  • Models, Biological
  • Saccharomyces cerevisiae / genetics*
  • Saccharomyces cerevisiae / physiology*
  • Time Factors

Substances

  • DNA, Mitochondrial