Regulation of translation initiation by FRAP/mTOR

Genes Dev. 2001 Apr 1;15(7):807-26. doi: 10.1101/gad.887201.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Androstadienes / pharmacology
  • Animals
  • Antineoplastic Agents / pharmacology
  • Binding Sites
  • Carrier Proteins / metabolism
  • Cell Division / genetics
  • Cell Division / physiology
  • Chromones / pharmacology
  • Drosophila Proteins*
  • Drosophila melanogaster / genetics
  • Drosophila melanogaster / metabolism
  • Energy Metabolism / genetics
  • Enzyme Inhibitors / pharmacology
  • Eukaryotic Cells / drug effects
  • Eukaryotic Cells / metabolism
  • Eukaryotic Initiation Factor-4G
  • Eukaryotic Initiation Factors*
  • Fungal Proteins / metabolism
  • Gene Expression Regulation / drug effects
  • Gene Expression Regulation / physiology*
  • Insect Proteins / genetics
  • Insect Proteins / metabolism
  • Insulin / pharmacology
  • Macromolecular Substances
  • Mammals / genetics
  • Mammals / metabolism
  • Mice
  • Morpholines / pharmacology
  • Neoplasm Proteins / antagonists & inhibitors
  • PTEN Phosphohydrolase
  • Peptide Fragments / metabolism
  • Peptide Initiation Factors / metabolism
  • Phosphatidylinositol 3-Kinases / physiology
  • Phosphoinositide-3 Kinase Inhibitors
  • Phosphoprotein Phosphatases / metabolism
  • Phosphoric Monoester Hydrolases / metabolism
  • Phosphorylation / drug effects
  • Phosphotransferases (Alcohol Group Acceptor) / genetics
  • Phosphotransferases (Alcohol Group Acceptor) / metabolism
  • Protein Biosynthesis* / drug effects
  • Protein Biosynthesis* / physiology
  • Protein Kinase Inhibitors
  • Protein Kinases / chemistry
  • Protein Kinases / genetics
  • Protein Kinases / physiology*
  • Protein Processing, Post-Translational / drug effects
  • Protein Serine-Threonine Kinases*
  • Protein Structure, Tertiary
  • Proto-Oncogene Proteins / metabolism
  • Proto-Oncogene Proteins c-akt
  • RNA, Messenger / genetics
  • Saccharomyces cerevisiae / genetics
  • Saccharomyces cerevisiae / metabolism
  • Saccharomyces cerevisiae Proteins
  • Signal Transduction / drug effects
  • Sirolimus / pharmacology
  • Species Specificity
  • Structure-Activity Relationship
  • TOR Serine-Threonine Kinases
  • Tacrolimus Binding Protein 1A / metabolism
  • Tumor Suppressor Proteins*
  • Wortmannin

Substances

  • Androstadienes
  • Antineoplastic Agents
  • Carrier Proteins
  • Chromones
  • Drosophila Proteins
  • Eif4ebp2 protein, mouse
  • Eif4g1 protein, mouse
  • Enzyme Inhibitors
  • Eukaryotic Initiation Factor-4G
  • Eukaryotic Initiation Factors
  • Fungal Proteins
  • Insect Proteins
  • Insulin
  • Macromolecular Substances
  • Morpholines
  • Neoplasm Proteins
  • Peptide Fragments
  • Peptide Initiation Factors
  • Phosphoinositide-3 Kinase Inhibitors
  • Protein Kinase Inhibitors
  • Proto-Oncogene Proteins
  • RNA, Messenger
  • Saccharomyces cerevisiae Proteins
  • TIF4631 protein, S cerevisiae
  • Tumor Suppressor Proteins
  • eIF-4B
  • 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one
  • Protein Kinases
  • Phosphotransferases (Alcohol Group Acceptor)
  • target of rapamycin protein, Drosophila
  • mTOR protein, mouse
  • Protein Serine-Threonine Kinases
  • Proto-Oncogene Proteins c-akt
  • TOR Serine-Threonine Kinases
  • Phosphoprotein Phosphatases
  • Phosphoric Monoester Hydrolases
  • PTEN Phosphohydrolase
  • Tacrolimus Binding Protein 1A
  • Sirolimus
  • Wortmannin