Selective inhibition of NF-AT DNA binding by the short-chain fatty acid n-butyrate

Transplant Proc. 2001 Feb-Mar;33(1-2):197-8. doi: 10.1016/s0041-1345(00)01973-4.

Authors

C Diakos¹, E Prieschl, M Säemann, G Böhmig, T Baumruker, G Zlabinger

Affiliation

¹ Institute of Immunology, Department of Internal Medicine III, University of Vienna, Vienna, Austria.

PMID: 11266777
DOI: 10.1016/s0041-1345(00)01973-4

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Butyrates / pharmacology*
Calcium / metabolism
Cell Division / drug effects
DNA-Binding Proteins / drug effects*
Genes, Reporter
Humans
Interleukin-2 / biosynthesis*
Interleukin-2 / genetics
Jurkat Cells
Mitogen-Activated Protein Kinase Kinases / metabolism
Mitogen-Activated Protein Kinases / metabolism
NFATC Transcription Factors
Nuclear Proteins*
Phosphorylation
Signal Transduction / drug effects
T-Lymphocytes / drug effects*
T-Lymphocytes / immunology
Transcription Factor AP-1 / genetics
Transcription Factors / drug effects*
Transcription, Genetic / drug effects
p38 Mitogen-Activated Protein Kinases

Substances

Butyrates
DNA-Binding Proteins
Interleukin-2
NFATC Transcription Factors
Nuclear Proteins
Transcription Factor AP-1
Transcription Factors
Mitogen-Activated Protein Kinases
p38 Mitogen-Activated Protein Kinases
Mitogen-Activated Protein Kinase Kinases
Calcium