Effect of concomitant or very early statin administration on in-hospital mortality and reinfarction in patients with acute myocardial infarction

K A Bybee; R S Wright; B A Williams; J G Murphy; D R Holmes Jr; S L Kopecky

doi:10.1016/s0002-9149(00)01501-0

Effect of concomitant or very early statin administration on in-hospital mortality and reinfarction in patients with acute myocardial infarction

Am J Cardiol. 2001 Mar 15;87(6):771-4, A7. doi: 10.1016/s0002-9149(00)01501-0.

Authors

K A Bybee¹, R S Wright, B A Williams, J G Murphy, D R Holmes Jr, S L Kopecky

Affiliation

¹ Department of Internal Medicine, Mayo Physician Alliance for Clinical Trials, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA.

PMID: 11249901
DOI: 10.1016/s0002-9149(00)01501-0

Abstract

In a retrospective analysis, 66 patients identified as having received a statin drug within 24 hours of admission for acute myocardial infarction were matched 3:1 with a control group of 198 patients not treated with a statin agent. End points of in-hospital mortality and in-hospital reinfarction were significantly lower in the statin-treated group, pointing to a benefit from very early statin treatment in acute myocardial infarction.

MeSH terms

Aged
Drug Administration Schedule
Female
Hospital Mortality
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors / administration & dosage*
Hypolipidemic Agents / administration & dosage*
Male
Myocardial Infarction / mortality*
Myocardial Infarction / therapy
Recurrence
Retrospective Studies
Survival Rate
Time Factors

Substances

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Hypolipidemic Agents