Liver transplantation in a child with severe hypercholesterolaemia in Alagille syndrome

Ann Acad Med Singap. 2001 Jan;30(1):44-7.

Abstract

Introduction: Liver transplantation is a curative treatment modality in children with end stage liver disease in Alagille syndrome.

Clinical picture: We report a 3-year-old child with this condition who had severe hypercholesterolaemia, pruritus and extensive xanthomatosis.

Treatment: Liver transplantation was performed in this patient.

Outcome: He recovered well with normalisation of his lipid profile. This procedure also resulted in resolution of the disfiguring xanthomatosis.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alagille Syndrome / complications
  • Alagille Syndrome / diagnosis
  • Alagille Syndrome / surgery*
  • Child, Preschool
  • Follow-Up Studies
  • Humans
  • Hypercholesterolemia / complications
  • Hypercholesterolemia / diagnosis
  • Hypercholesterolemia / surgery*
  • Liver Transplantation / methods*
  • Male
  • Severity of Illness Index
  • Treatment Outcome