Multisite comparison of reproducibility and recovery from the standard and ultrasensitive Roche AMPLICOR HIV-1 MONITOR assays

J Clin Microbiol. 2001 Mar;39(3):1121-3. doi: 10.1128/JCM.39.3.1121-1123.2001.

Abstract

Reproducibility and recovery from the standard and ultrasensitive Roche AMPLICOR HIV-1 MONITOR kits were compared in 19 laboratories. The results were generally similar, but the consistently low level of recovery from the ultrasensitive assay in one laboratory points to the need to include external controls in order to track assay performance.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • HIV Infections / diagnosis*
  • HIV Infections / virology
  • HIV-1 / physiology*
  • Humans
  • Internal-External Control
  • Laboratories / standards
  • Quality Control
  • RNA, Viral / blood*
  • Reagent Kits, Diagnostic / standards
  • Reproducibility of Results
  • Viral Load

Substances

  • RNA, Viral
  • Reagent Kits, Diagnostic