Extensions to a procedure for generating locally identifiable reparameterisations of unidentifiable systems

Math Biosci. 2000 Dec;168(2):137-59. doi: 10.1016/s0025-5564(00)00047-x.

Abstract

In this paper extensions to an existing procedure for generating locally identifiable reparameterisations of unidentifiable systems are presented. These extensions further formalise the constructive nature of the methodology and lend themselves to application within symbolic manipulation packages. The extended reparameterisation procedure is described in detail and is illustrated with application to two known non-trivial examples of unidentifiable systems of practical relevance.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bioreactors
  • Coloring Agents / chemistry
  • Models, Biological*
  • Sulfobromophthalein / chemistry

Substances

  • Coloring Agents
  • Sulfobromophthalein