Favorable long-term outcome in adult genitourinary low-grade sarcoma

Urology. 2000 Sep 1;56(3):373-7. doi: 10.1016/s0090-4295(00)00704-4.

Abstract

Objectives: To report our experience treating sarcomas in 20 consecutive patients.

Methods: Pretreatment and follow-up data were obtained from 20 adult patients consecutively treated between 1992 and 1998 for primary or locally recurrent genitourinary sarcoma.

Results: Eight patients (40%) were classified as having high-grade and 12 (60%) low-grade disease. Except for 3 patients, the primary treatment was surgery alone. The median follow-up was 52 months. The actuarial disease-specific 5-year survival rate was 84% in all patients and was 100% for patients with Memorial Sloan Kettering Cancer Center (MSKCC) Stages 1-2 and 54% in MSKCC Stages 3-4. The disease-specific survival was significantly better in low-grade tumors (log-rank test, P = 0.0063) and inguinal-scrotal tumors (P = 0.019), tumors 5 cm or less (P = 0.039), and MSKCC Stages 1-2 tumors (P = 0.0035).

Conclusions: The results of this study with a high proportion of low-grade, low-stage, and inguinal-scrotal sarcomas demonstrate the favorable prognosis of these subgroups.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Female
  • Genital Neoplasms, Male / mortality
  • Genital Neoplasms, Male / pathology
  • Genital Neoplasms, Male / therapy
  • Humans
  • Kidney Neoplasms / mortality
  • Kidney Neoplasms / pathology
  • Kidney Neoplasms / therapy
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Prognosis
  • Sarcoma* / mortality
  • Sarcoma* / pathology
  • Sarcoma* / therapy
  • Treatment Outcome
  • Urinary Bladder Neoplasms / mortality
  • Urinary Bladder Neoplasms / pathology
  • Urinary Bladder Neoplasms / therapy
  • Urogenital Neoplasms* / mortality
  • Urogenital Neoplasms* / pathology
  • Urogenital Neoplasms* / therapy