Chlorambucil-induced acute hepatic failure in a patient with membranous nephropathy

Am J Kidney Dis. 2000 Aug;36(2):401-4. doi: 10.1053/ajkd.2000.8995.

Abstract

We present the case of a 23-year-old woman with membranous nephropathy who developed acute hepatic failure after being administered chlorambucil for a month.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Alkylating Agents / adverse effects*
  • Alkylating Agents / therapeutic use
  • Chlorambucil / adverse effects*
  • Chlorambucil / therapeutic use
  • Female
  • Glomerulonephritis, Membranous / drug therapy*
  • Glomerulonephritis, Membranous / pathology
  • Humans
  • Kidney / pathology
  • Liver / pathology
  • Liver Failure, Acute / chemically induced*
  • Liver Failure, Acute / pathology

Substances

  • Alkylating Agents
  • Chlorambucil