Ligands for glutamate receptors: design and therapeutic prospects

J Med Chem. 2000 Jul 13;43(14):2609-45. doi: 10.1021/jm000007r.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Drug Design
  • Excitatory Amino Acid Agonists / chemistry*
  • Excitatory Amino Acid Agonists / metabolism
  • Excitatory Amino Acid Agonists / pharmacology
  • Excitatory Amino Acid Agonists / therapeutic use
  • Excitatory Amino Acid Antagonists / chemistry*
  • Excitatory Amino Acid Antagonists / metabolism
  • Excitatory Amino Acid Antagonists / pharmacology
  • Excitatory Amino Acid Antagonists / therapeutic use
  • Humans
  • Ligands
  • N-Methylaspartate / agonists
  • N-Methylaspartate / antagonists & inhibitors
  • N-Methylaspartate / chemistry
  • N-Methylaspartate / metabolism
  • Receptors, AMPA / agonists
  • Receptors, AMPA / antagonists & inhibitors
  • Receptors, AMPA / chemistry
  • Receptors, AMPA / metabolism
  • Receptors, Glutamate / chemistry
  • Receptors, Glutamate / drug effects*
  • Receptors, Glutamate / metabolism
  • Receptors, Kainic Acid / agonists
  • Receptors, Kainic Acid / antagonists & inhibitors
  • Receptors, Kainic Acid / chemistry
  • Receptors, Kainic Acid / metabolism
  • Receptors, Metabotropic Glutamate / agonists
  • Receptors, Metabotropic Glutamate / antagonists & inhibitors
  • Receptors, Metabotropic Glutamate / chemistry
  • Receptors, Metabotropic Glutamate / metabolism
  • Synapses / metabolism

Substances

  • Excitatory Amino Acid Agonists
  • Excitatory Amino Acid Antagonists
  • Ligands
  • Receptors, AMPA
  • Receptors, Glutamate
  • Receptors, Kainic Acid
  • Receptors, Metabotropic Glutamate
  • N-Methylaspartate