Renin-producing hepatoblastoma

J Pediatr Hematol Oncol. 2000 Jan-Feb;22(1):78-80. doi: 10.1097/00043426-200001000-00015.

Abstract

Renin-producing tumors of extrarenal origin are rare in children. An 8-year-old boy with hepatoblastoma and hypertension associated with a high plasma renin level is reported. After chemotherapy, the plasma renin level normalized and the hypertension spontaneously resolved. The patient underwent surgery, and a right trisegmentectomy of the liver and a partial resection of the second and third segments were performed. The tumor was as shown the source of renin by immunohistochemical study and reverse transcriptase-polymerase chain reaction.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Hepatoblastoma / blood
  • Hepatoblastoma / metabolism*
  • Humans
  • Hypertension / blood
  • Liver Neoplasms / blood
  • Liver Neoplasms / metabolism*
  • Male
  • Renin / biosynthesis*
  • Renin / blood

Substances

  • Renin