cDNA sequence analysis of a novel member of the three loop protein family from the Chinese continental banded krait

Biosci Biotechnol Biochem. 1999 May;63(5):940-2. doi: 10.1271/bbb.63.940.

Abstract

The cDNA encoding a novel three loop protein was cloned from cellular RNA isolated from the venom gland of Bungarus multicinctus multicinctus by RT-PCR. The mature protein has 82 amino acid residues. It shared only 25-38% similarity with some cardiotoxins and did not have sequence similarity with neurotoxins, while its cDNA was about 70% similar to both the cDNAs encoding neurotoxins and the cDNAs encoding cardiotoxins.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Bungarotoxins / chemistry
  • Bungarotoxins / genetics*
  • Bungarus
  • DNA, Complementary
  • Elapid Venoms / chemistry*
  • Molecular Sequence Data
  • Phylogeny
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sequence Homology, Amino Acid

Substances

  • BMLCL protein, Bungarus multicinctus multicinctus
  • Bungarotoxins
  • DNA, Complementary
  • Elapid Venoms

Associated data

  • GENBANK/AJ007741