[Hydro-MRT with fast sequences in Crohn's disease: a comparison with fractionated gastrointestinal passage]

Rofo. 1999 Apr;170(4):338-46. doi: 10.1055/s-2007-1011051.
[Article in German]

Abstract

Purpose: To compare the value of hydro-MRI with that of barium studies in patients with Crohn's disease.

Materials and methods: After an oral bowel opacification using 1000 ml of a 2.5% mannitol solution, axial and coronal breath-hold sequences (T2W HASTE +/- FS, contrast-enhanced T1W FLASH FS) were acquired in 46 patients with Crohn's disease at 1.0 T. The findings of hydro-MRI were compared with those of barium studies.

Results: In the stomach and the small bowel, hydro-MRI and barium studies demonstrated similar numbers of Crohn's involvements (39 vs. 36); in the colon, hydro-MRI showed clearly more affections (23 vs. 10). Hydro-MRI showed 12.7 cm of inflamed bowel per patient, on average (barium studies: 10.4 cm; p = 0.004). There was a good agreement between the two methods regarding the assessment of the extent of Crohn's disease and the severity of bowel stenoses (r = 0.89 and 0.88, respectively).

Conclusions: For the assessment of Crohn's disease, hydro-MRI is preferable to the barium study because of the superior imaging quality and the lack of radiation exposure.

Publication types

  • Comparative Study

MeSH terms

  • Administration, Oral
  • Adolescent
  • Adult
  • Aged
  • Barium Sulfate / administration & dosage
  • Butylscopolammonium Bromide
  • Contrast Media / administration & dosage
  • Crohn Disease / diagnosis*
  • Digestive System / diagnostic imaging*
  • Female
  • Gadolinium DTPA
  • Humans
  • Magnetic Resonance Imaging / instrumentation
  • Magnetic Resonance Imaging / methods*
  • Magnetic Resonance Imaging / statistics & numerical data
  • Male
  • Middle Aged
  • Radiography
  • Statistics, Nonparametric
  • Time Factors

Substances

  • Contrast Media
  • Barium Sulfate
  • Butylscopolammonium Bromide
  • Gadolinium DTPA