Low incidence of candidaemia among neutropenic patients treated for haematological diseases

Scand J Infect Dis. 1998;30(5):489-93. doi: 10.1080/00365549850161502.

Abstract

Candida colonization and haematogenous infection were studied retrospectively in 277 patients with haematological diseases by reviewing the microbiological reports of fungal surveillance and blood cultures over a 4-year period. Most patients (83%) were colonized by Candida and in the majority (68%) the same Candida species was isolated from at least 2 body sites. However, candidaemia was diagnosed in only 3 patients. During the same period invasive aspergillosis was diagnosed in 7 patients. Possible causes for the low incidence of candidaemia were fluconazole prophylaxis, empirical amphotericin B and strict indication for antibacterial therapy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Candidiasis / complications
  • Candidiasis / epidemiology*
  • Candidiasis / prevention & control
  • Female
  • Fungemia / complications
  • Fungemia / epidemiology*
  • Fungemia / prevention & control
  • Hematologic Diseases / complications*
  • Humans
  • Incidence
  • Male
  • Middle Aged
  • Neutropenia / complications*
  • Opportunistic Infections / complications
  • Opportunistic Infections / epidemiology*
  • Opportunistic Infections / prevention & control
  • Retrospective Studies